Our Mission

Our goal is to leverage the natural learning mechanisms of cortical circuits to develop high-precision, modular, and efficient brain-computer interfaces. Advances in the BCI field have largely been driven by increasingly high-bandwidth recordings and intricate machine-learning algorithms. In the Gonzales Lab, we take a circuit-focused approach. We believe cortical networks and microcircuits hold secrets that can unlock powerful new capabilities for neuroprosthetics. By revealing how these circuits learn the artificial task of BCI control, we can inform the design of clinical neural interfaces and advanced decoding algorithms.

Our Approach

Microfabricated Tools

We design & fabricate flexible, transparent brain-computer interfaces

High-Density Electrophysiology

Our interfaces enable long-term, stable recordings

Novel Tasks

We create unconventional BCI behavioral tasks to probe the underlying mechanisms of neural control

Multiphoton Imaging

We combine two-photon imaging and electrophysiology in vivo

Circuit Manipulations

We use optogenetic, pharmacological, and electrical methods to selectively manipulate circuit components

Our Philosophy

We are passionate about producing discoveries with multifaceted impacts on neuroscience, neuroengineering, and human health. Yet, we also recognize that science is built upon by a collection of people. We believe that building a culture of scientific excellence requires a culture of support, mentorship, and empowerment. We aim to accomplish these four core goals into our work:

We want to be healthy. We want to be productive. We want to be efficient. We want to have fun.

It’s that simple. We believe that by intentionally working towards these four goals, we can both produce meaningful scientific discoveries and build a culture of excellence that centers on people. To learn more about lab philosophies, please see our Handbook.